\documentclass{article}
% \usepackage{unicode-math}
\directlua{require'luamml-tex'}
\RegisterFamilyMapping\symsymbols{oms}
\RegisterFamilyMapping\symletters{oml}
\begin{document}
\[
  ax^2+b+c=0
\]
\[
  x = \frac{-b \pm \sqrt{b^2-4ac}}{2a}.
\]
\[
  \sum_a\underline c\dot bc'
\]

Es gilt $\sin(x)-\sin(x+2\pi)=0$.
\end{document}